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The effect of AA-signalling agonists and antagonists on the viability of SH-SY5Y neuroblastoma cells treated with ATRA (dose-response) in combination with fixed doses of the 5-LO inhibitors celecoxib or MK886.
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The effect of AA-signalling agonists and antagonists on the viability of SH-SY5Y neuroblastoma cells treated with ATRA (dose-response) in combination with fixed doses of the 5-LO inhibitors celecoxib or MK886.

Journal: PLoS ONE

Article Title: Cell Survival Signalling through PPARδ and Arachidonic Acid Metabolites in Neuroblastoma

doi: 10.1371/journal.pone.0068859

Figure Lengend Snippet: The effect of AA-signalling agonists and antagonists on the viability of SH-SY5Y neuroblastoma cells treated with ATRA (dose-response) in combination with fixed doses of the 5-LO inhibitors celecoxib or MK886.

Article Snippet: All- trans RA (ATRA), AACOCF3, GSK0660, MK886 and Prostaglandin E2 (PGE2) were from Sigma-Aldrich, PD-146176 from Enzo Life Sciences (Farmindale, NY), celecoxib from Pfizer (NY), baicalein, 5-oxo-ETE and leukotriene A4 (LTA4) methyl ester were from Cayman Chemicals (Ann Arbor, MI).

Techniques: